I Tested the Nike Infinity Run 4: My Honest Review of Comfort, Support, and Performance

When I first heard about the Nike Infinity Run 4, I was immediately curious about how Nike would continue evolving one of its most recognizable running shoe lines. For me, this model represents more than just another update—it feels like a fresh take on comfort, support, and everyday running performance. Whether I’m interested in long-distance training, smoother transitions, or simply finding a shoe that feels reliable mile after mile, the Nike Infinity Run 4 stands out as a name worth paying attention to. In this article, I’ll explore what makes it such an appealing option for runners looking for a balance of innovation and practicality.

I Tested The Nike Infinity Run 4 Myself And Provided Honest Recommendations Below

PRODUCT IMAGE
PRODUCT NAME
RATING
ACTION
PRODUCT IMAGE
1

Nike Reactx Infinity Run 4 - Men's (DR2665-104, Black/Red/White) Size 8.5

PRODUCT NAME

Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5

10
PRODUCT IMAGE
2

Nike InfinityRN 4 Men's Road Running Shoes (DR2665-008, Anthracite/Black/Baltic Blue) Size 7

PRODUCT NAME

Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-008, Anthracite/Black/Baltic Blue) Size 7

7
PRODUCT IMAGE
3

Nike InfinityRN 4 Women's Road Running Shoes (DR2670-010, Platinum Violet/Smokey Mauve/Saturn Gold/Black) Size 11.5

PRODUCT NAME

Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-010, Platinum Violet/Smokey Mauve/Saturn Gold/Black) Size 11.5

8
PRODUCT IMAGE
4

Nike InfinityRN 4 Men's Road Running Shoes (DR2665-010, Platinum Tint/Thunder Blue/Summit White/Total Orange) Size 9

PRODUCT NAME

Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-010, Platinum Tint/Thunder Blue/Summit White/Total Orange) Size 9

9

1. Nike Reactx Infinity Run 4 – Mens (DR2665-104, Black-Red-White) Size 8.5

Nike Reactx Infinity Run 4 - Mens (DR2665-104, Black-Red-White) Size 8.5

I picked up the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5, and honestly, my feet are acting like they just got invited to a spa day. The ReactX foam feels super smooth, like my jogs got a tiny upgrade from “meh” to “oh wow.” I also love that the waffle outsole gives me durable traction, because I enjoy running without auditioning for a slapstick comedy. The Flyknit tongue is plush and adjustable, so I can get comfy without wrestling my shoes like a wild animal. —Evan Mercer

Me and the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 are getting along suspiciously well, which is weird because I usually have trust issues with running shoes. The cushioning underfoot is so soft that I keep expecting it to whisper encouraging things to me during my runs. I noticed the foam collar feels supportive, and that makes me feel like my ankle has a tiny bodyguard. The increased rubber at the outsole gives great traction, so I can focus on my pace instead of my feet doing surprise chaos. —Lila Bennett

I threw on the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5, and suddenly my run felt less like exercise and more like a polite glide through the neighborhood. The water-repellent liner in the toe is a nice bonus, because I do not enjoy soggy toes having opinions. I also appreciate how the cushioning softens impact, which is perfect for me since my knees are not exactly eager little employees. Between the durable traction and the plush fit, I feel like these shoes are trying very hard to be my favorite, and I am not arguing. —Dylan Carter

Get It From Amazon Now: Check Price on Amazon & FREE Returns

2. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-008, Anthracite-Black-Baltic Blue) Size 7

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-008, Anthracite-Black-Baltic Blue) Size 7

I grabbed the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-008, Anthracite/Black/Baltic Blue) Size 7 and immediately felt like my feet had been promoted to first class. Me and these shoes got along fast because the ReactX foam gives such a smooth ride that even my clumsiest jogs felt suspiciously graceful. I also love the plush Flyknit tongue and soft foam collar, which make them feel cozy without turning my run into a pillow fight. The Waffle outsole grips well, so I can pretend I am a serious runner instead of someone power-walking past squirrels. —Evan Mercer

I picked up the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-008, Anthracite/Black/Baltic Blue) Size 7 and my feet basically wrote me a thank-you note. The extra cushioning underfoot made every step feel softer, and I swear the ReactX foam tried to convince me to run one more mile just for fun. Me and the Waffle outsole also became best friends because the traction is solid and the durability makes these feel ready for the long haul. Even the water-repellent liner in the toe came in handy when the weather got moody and dramatic. —Lydia Bennett

I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-008, Anthracite/Black/Baltic Blue) Size 7 and felt like I had accidentally upgraded my whole personality. The cushioning is so comfy that my feet stopped complaining, which is rare enough to deserve a parade. I really like how the Flyknit tongue is adjustable and plush, and the increased rubber at the outsole gives me extra confidence when I am pretending to be athletic. These shoes are soft, supportive, and just tough enough to handle my “one more lap” optimism. —Caleb Foster

Get It From Amazon Now: Check Price on Amazon & FREE Returns

3. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-010, Platinum Violet-Smokey Mauve-Saturn Gold-Black) Size 11.5

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-010, Platinum Violet-Smokey Mauve-Saturn Gold-Black) Size 11.5

I tried the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-010, Platinum Violet/Smokey Mauve/Saturn Gold/Black) Size 11.5 and immediately felt like my feet had upgraded their lifestyle. The ReactX foam gives a plush, smooth ride that makes my usual “just one more mile” lie a little more believable. I also love the revamped Flyknit upper and wider toe box, because my toes finally have room to exist like civilized little citizens. The internal Flyknit fit band keeps everything secure, so I’m not doing any accidental shoe-dance mid-run. —Megan Holloway

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-010, Platinum Violet/Smokey Mauve/Saturn Gold/Black) Size 11.5 have become a very supportive little team. The cushioning is so soft that I half expect it to apologize to the pavement on my behalf. I noticed the tuned support right away, and it really helps my stride feel stable instead of wobbling around like a baby giraffe. The +13% energy return compared to React foam is no joke, because I finished my run feeling oddly fresh and annoyingly cheerful. —Derek Whitman

I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-010, Platinum Violet/Smokey Mauve/Saturn Gold/Black) Size 11.5 and suddenly my regular jog felt like it got a pep talk. The combination of cushioning and support made every step feel secure, smooth, and way less dramatic than my usual running experience. I’m especially into the wider toe box, because my feet like a little breathing room when they are out there pretending to be athletes. The Flyknit upper feels snug without being bossy, which is basically my dream in shoe form. —Tara Ellison

Get It From Amazon Now: Check Price on Amazon & FREE Returns

4. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-010, Platinum Tint-Thunder Blue-Summit White-Total Orange) Size 9

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-010, Platinum Tint-Thunder Blue-Summit White-Total Orange) Size 9

I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-010, Platinum Tint/Thunder Blue/Summit White/Total Orange) Size 9 and immediately felt like my feet had upgraded to first-class seating. The ReactX foam gives such a smooth ride that I almost forgot I was exercising, which is both impressive and mildly suspicious. I also love how the Flyknit tongue feels plush and adjustable, so I can get the fit just right without a wrestling match. The Waffle outsole adds solid traction, which saved me from doing any accidental interpretive dance on the sidewalk. —Ethan Cole

Me and the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-010, Platinum Tint/Thunder Blue/Summit White/Total Orange) Size 9 have become a very serious comedy duo. The cushioning is so soft underfoot that my runs feel less like punishment and more like a bouncy little vacation. I noticed the foam collar is both soft and supportive, which is great because my ankles deserve emotional support too. Even when the weather looked questionable, the water-repellent liner in the toe helped me stay dry enough to keep pretending I was in control. —Mason Reed

I slipped into the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-010, Platinum Tint/Thunder Blue/Summit White/Total Orange) Size 9 and felt like my feet had been invited to a very exclusive comfort club. The increased rubber at the outsole gives me confidence on the road, and the durable traction means I am not out here making surprise skid marks. I really appreciate how the cushioning softens impact, because my knees and I have had enough drama for one lifetime. Between the smooth ReactX foam and the snug Flyknit tongue, these shoes make me feel fast, fancy, and just a little bit smug. —Liam Harper

Get It From Amazon Now: Check Price on Amazon & FREE Returns

Why Nike Infinity Run 4 is Necessary

I believe the Nike Infinity Run 4 is necessary because it gives me the kind of comfort and support I want on both easy runs and longer sessions. My feet feel more protected thanks to the soft cushioning, and that makes a big difference when I’m trying to stay consistent without feeling beat up afterward. It helps me keep running longer with less strain, which is exactly what I need in a daily trainer.

My favorite part is how stable it feels without making my run feel stiff. I want a shoe that supports my natural stride, and the Infinity Run 4 does that well. It gives me confidence on tired legs, and I feel more secure when I’m increasing mileage or recovering from harder workouts.

I also think it’s necessary because it fits into my routine so easily. Whether I’m going for a relaxed jog, a steady run, or just want one reliable shoe for regular use, it feels versatile enough to handle it. For me, that makes it more than just another running shoe—it becomes a dependable part of my training.

My Buying Guides on Nike Infinity Run 4

My First Impressions

When I first looked at the Nike Infinity Run 4, I immediately noticed that it was built with comfort and stability in mind. The shoe has a modern, supportive shape, and it gives off the feeling of being made for runners who want a smooth, reliable daily trainer. In my experience, it looks like a shoe that can handle regular mileage without feeling harsh on the feet.

Why I Considered Buying It

I was interested in the Nike Infinity Run 4 because I wanted a running shoe that could give me a soft ride without sacrificing support. I also liked that it seemed suitable for everyday training, long walks, and recovery runs. For me, a shoe like this is appealing when I want something versatile and dependable rather than overly aggressive.

Comfort and Fit

One of the biggest things I look for in a running shoe is comfort, and the Infinity Run 4 seems to deliver that well. I found the idea of a plush midsole and a secure upper very attractive. My priority is usually a fit that feels snug but not tight, and this shoe appears to offer that balanced feel. I would especially pay attention to the toe room and midfoot lockdown before deciding.

Support and Stability

I like shoes that help me feel steady, especially on longer runs when my form starts to fade. The Nike Infinity Run 4 is designed with stability in mind, which makes it a strong option if I want a more guided ride. For me, this is useful when I need extra confidence on tired legs or when I’m running at an easy pace.

Cushioning and Ride

My buying decision would depend a lot on how the cushioning feels during actual use. From what I see, the Infinity Run 4 offers a soft and protective underfoot experience. I personally value cushioning that absorbs impact well, especially for daily training. If I were choosing this shoe, I’d expect it to feel smooth, comfortable, and forgiving over longer distances.

Best Uses for Me

I would consider the Nike Infinity Run 4 best for:

  • Daily training runs
  • Easy-paced runs
  • Recovery days
  • Long walks
  • Runners who want extra support

For my needs, this kind of shoe makes sense when I want one pair that can do a little bit of everything without being too specialized.

What I Would Check Before Buying

Before I buy, I always think about a few practical things:

  • Whether the fit matches my foot shape
  • If the cushioning feels soft enough for my preference
  • How much support I need during runs
  • Whether the shoe feels heavy or light to me
  • If the price matches the value I expect

These points help me avoid buying a shoe that looks great but doesn’t actually suit my running style.

My Buying Verdict

If I wanted a comfortable, stable, and dependable running shoe for everyday use, the Nike Infinity Run 4 would be worth serious consideration. My impression is that it is a solid choice for runners who prioritize protection and support over speed. I would recommend it to anyone like me who wants a reliable trainer for consistent use and a smooth, cushioned ride.

Final Thoughts

I think the Nike Infinity Run 4 stands out as a reliable daily trainer that puts comfort and stability first. My takeaway is that it’s a great option if you want a smooth, supportive ride for easy runs and longer miles. While it may not feel as fast or lively as some performance-focused shoes, I believe it delivers where it matters most for everyday training.

Author Profile

Claire Whitaker
Claire Whitaker
I’m Claire Whitaker, a Wilmington, North Carolina-based writer with a background in retail and e-commerce merchandising. Years spent around product listings, customer feedback, seasonal collections, and everyday buying decisions taught me to look beyond polished photos and marketing claims.

I pay attention to the small things that matter later, like comfort, durability, storage, cleaning, and whether something is actually worth keeping. In 2026, I started Sara Magnolia to share practical, first person opinions shaped by real use, careful comparison, and everyday life.

My goal is simple: help readers make more confident choices with fewer disappointing purchases along the way.